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Cytochalasin C

ALX-380-069-M001 1 mg 81.00 USD
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Antibiotic. Disrupts the actin microfilament cytoskeleton and inhibits the cytoplasmic dividing of a cell. Has been found to be ten times less toxic in mice than cytochalasin D (Prod. No. BML-T109) but with essentially the same biological effectiveness against cells in culture.

Product Details

Source:Isolated from Metarhizium anisopliae.
MI:14: 2790
Purity:≥98% (TLC)
Appearance:White to off-white powder.
Solubility:Soluble in DMSO, 100% ethanol or dichloromethane.
Long Term Storage:-20°C
Handling:Protect from light.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Alteration in cell morphology triggers transforming growth factor-beta 1, collagenase, and tissue inhibitor of metalloproteinases-I expression in normal and hypertrophic scar fibroblasts: M. Varedi, et al.; J. Invest. Dermatol. 104, 118 (1995), Abstract;
Actin assembly activity of cytochalasins and cytochalasin analogs assayed using fluorescence photobleaching recovery: E.A. Walling, et al.; Arch. Biochem. Biophys. 264, 321 (1988), Abstract;

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