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Tetracycline . hydrochloride

Antibiotic and anti-inflammatory
ALX-380-060-G005 5 g 38.00 USD
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Broad-spectrum antibiotic with anti-inflammatory activity. Blocks bacterial protein synthesis by inhibiting binding of aminoacyl tRNA to A-site of ribosomes. Tetracycline-controlled systems are used to control gene expression on transgenic mice. Marker of bone formation.

Product Specification

Formula:C22H24N2O8 . HCl
MW:444.5 . 36.5
MI:14: 9196
Purity:≥98% (HPLC)
Appearance:Yellow crystalline solid.
Activity:Potency is ≥950 µg/mg (on dry basis).
Solubility:Soluble in water, methanol or 100% ethanol.
Long Term Storage:+4°C
Handling:Protect from light and moisture.
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Product Literature References

Anti-inflammatory activity of tetracyclines: G. Webster & J. Q. Del Rosso; Dermatol. Clin. 25, 133 (2007), Abstract;
Tetracycline-controlled genetic switches: R. Sprengel & M. T. Hasan; Handb. Exp. Pharmacol. 178, 49 (2007), Abstract;
A novel tetracycline labeling schedule for longitudinal evaluation of the short-term effects of anabolic therapy with a single iliac crest bone biopsy: early actions of teriparatide: R. Lindsay, et al.; J. Bone Miner. Res. 21, 366 (2006), Abstract;
Tetracyclines: nonantibiotic properties and their clinical implications: A. N. Sapadin & R. Fleischmajer; J. Am. Acad. Dermatol. 54, 258 (2006), Abstract;
Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance: I. Chopra & M. Roberts; Microbiol. Mol. Biol. Rev. 65, 232 (2001), Abstract;
Clinical and laboratory observations of a new antibiotic, tetracycline: M. Finland, et al.; J. Am. Med. Assoc. 154, 561 (1954), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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