Aminoglycoside antibiotic with broad antibacterial spectrum, including mycobacteria, many Gram-positive and most Gram-negative bacteria. Inhibits bacterial protein synthesis. Kanamycin resistance is widely used as a selection marker for obtaining transgenic plants.
Product Details
Formula: | C18H36N4O11 . H2SO4 |
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MW: | 484.5 . 98.1 |
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Source: | Isolated from Streptomyces kanamyceticus. |
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CAS: | 25389-94-0 |
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MI: | 14: 5281 |
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Appearance: | White to off-white crystalline powder. |
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Activity: | ≥700 µg/mg |
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Solubility: | Soluble in water. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | +4°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Caspase-independent pathways of hair cell death induced by kanamycin in vivo: H. Jiang, et al.; Cell Death Differ.
13, 20 (2006),
Abstract;
Controversy associated with the common component of most transgenic plants - kanamycin resistance marker gene: S. Jelenic; Food Technol. Biotechnol. 41, 183 (2003), (Review),
Antimicrobial agents--Part II. The aminoglycosides: streptomycin, kanamycin, gentamicin, tobramycin, amikacin, neomycin: N. S. Brewer; Mayo Clin. Proc.
52, 675 (1977),
Abstract;
Biological studies on kanamycin: T. Takeuchi, et al.; J. Antibiot. (Tokyo)
10, 107 (1957),
Abstract;