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Enniatin B

Ionophore antibiotic
 
ALX-380-007-M001 1 mg 182.00 USD
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Ionophore antibiotic. Inhibitor of the S. cerevisiae ABC transporter Pdr5p.Inhibitor of acyl-CoA-cholesterol acyltransferase and of phosphodiesterase. Potential anticancer compound.

Product Details

Formula:C33H57N3O9
 
MW:639.8
 
Source:Isolated from Fusarium orthoceras var. enniatum.
 
CAS:917-13-5
 
MI:14: 3585
 
Purity:≥90% (HPLC)
 
Appearance:White to off-white crystalline solid.
 
Solubility:Soluble in DMSO or other organic solvents; almost insoluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 
380-007
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380-007

Product Literature References

Beauvericin and enniatin B effects on a human lymphoblastoid Jurkat T-cell model: L. Manyes, et al.; Food Chem. Toxicol. 115, 127 (2018), Abstract;
Mycotoxin occurrence on baled and pit silages collected in Co. Meath: C. McElinney, et al.; Irish J. Agr. Food. Res. 54, 87 (2015), Application(s): Liquid chromatography tandem mass spectrometry for Mycotoxin analysis, Full Text
Toxic indole alkaloids avrainvillamide and stephacidin B produced by a biocide tolerant indoor mold Aspergillus westerdijkiae: R. Mikkola, et al.; Toxicon. 99, 58 (2015), Application(s): Cell Culture , Abstract;
Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells: R. Dornetshuber, et al.; Chem. Res. Toxicol. 20, 465 (2007), Abstract;
Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae: K. Hiraga, et al.; Biochem. Biophys. Res. Commun. 328, 1119 (2005), Abstract;
Interaction of cyclic peptides and depsipeptides with calmodulin: K.A. Mereish, et al.; Pept. Res. 3, 233 (1990), Abstract;
"Sandwich" complexation in cyclopeptides and its implications in membrane processes: V.T. Ivanov; Ann. N. Y. Acad. Sci. 264, 221 (1975), Abstract;
Ionophore antibiotics produced by the fungus Fusarium orthoceras var. enniatum and other Fusaria: E. Gaumann, et al.; Experientia 3, 202 (1947),

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