Bromotyrosine derivative with antimycobacterial activity.
Product Details
| Formula: | C24H26Br4N4O8 |
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| MW: | 818.1 |
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| Source: | Isolated from sponge Aplysina cavernicola. |
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| CAS: | 28714-26-3 |
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| Purity: | ≥96% (HPLC) |
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| Identity: | Determined by 1H-NMR and ESI-MS. |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in DMSO or 100% ethanol. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Bioactive constituents from the marine crinoid Himerometra magnipinna: N. Shao, et al.; J. Nat. Prod.
70, 869 (2007),
Abstract;
Asymmetric synthesis of aerothionin, a marine dimeric spiroisoxazoline natural product, employing optically active spiroisoxazoline derivative: T. Ogamino, et al.; THL 47, 727 (2006),
Aerothionin, a bromotyrosine derivative with antimycobacterial activity from the marine sponge Aplysina gerardogreeni (Demospongia): R. Encarnacion-Dimayuga, et al.; Pharm. Biol.
41, 384 (2003),
Abstract;
Syntheses of the Marine Metabolites Verongamine, Hemibastadin-2, and Aerothionin Using the Cyano Ylide Coupling Methodology: H.H. Wasserman & J. Wang; J. Org. Chem.
63, 5581 (1998),
Abstract;
Exudation of biologically-active metabolites in the sponge Aplysina fistularis: R.P. Walker, et al.; Mar. Biol.
88, 27 (1985),
Abstract;
Total Syntheses of (±)-Aerothionin, (±)-Homoaerothionin, and (±)-Aerophobin-1: S. Nishiyama & S. Yamamura; Bull. Chem. Soc. Jpn.
58, 3453 (1985),
Abstract;
Full Text
Aerothionin and homoaerothionin: two tetrabromo spirocyclohexadienylisoxazoles from Verongia sponges: K. Moody, et al.; J. Chem. Soc., Perkin Trans. 1 18 (1972),
Abstract;
