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Thielavin B

Inhibitor of Glucose-6-phosphatase and PLC
 
ALX-350-340-MC05 0.5 mg 357.00 USD
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Fungal metabolite. Glucose-6-phosphatase inhibitor. Potent inhibitor of phospholipase C. Inhibits telomerase, viral reverse transcriptase, peptidoglycan formation and prostaglandin biosynthesis.

Product Specification

Formula:C31H34O10
 
MW:566.6
 
Source:Isolated from an unidentified fungus MST-FP1888.
 
CAS:71950-67-9
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 
350-340
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350-340

Product Literature References

Thielavins as glucose-6-phosphatase (G6Pase) inhibitors: producing strain, fermentation, isolation, structural elucidation and biological activitie: S. Sakemi, et al.; J. Antibiot. (Tokyo) 55, 941 (2002), Abstract;
Inhibition of telomerase activity by fungus metabolites, CRM646-A and thielavin B: K. Togashi, et al.; Biosci. Biotechnol. Biochem. 65, 651 (2001), Abstract; Full Text
Screening systems for detecting inhibitors of cell wall transglycosylation in Enterococcus. Cell wall transglycosylation inhibitors in Enterococcus: N. Mani, et al.; J. Antibiot. (Tokyo) 51, 471 (1998), Abstract;
The structures of thielavins A, B and C. Prostaglandin synthetase inhibitors from fungi: N. Kitahara, et al.; J. Antibiot. (Tokyo) 36, 599 (1983), Abstract;
Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola: N. Kitahara, et al.; J. Antibiot. (Tokyo) 34, 1562 (1981), Abstract;

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