Antineoplastic compound. Cytotoxic against stomach cancer cell lines. Shows antibacterial activity against Shigella sonnei and S. flexneri. Shows strong antioxidant activity and inhibits tyrosine phosphatase 1B (PTP1B) activity. Was shown to possess potent antidepressant properties.
Product Details
| Formula: | C20H16O5 |
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| MW: | 336.3 |
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| Source: | Isolated from Psoralea corylifolia. |
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| CAS: | 18642-23-4 |
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| Purity: | ≥97% (HPLC) |
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| Identity: | Determined by 1H-NMR, 13C-NMR and MS. |
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| Appearance: | Yellow oily solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice: L.T. Yi, et al.; Prog. Neuropsychopharmacol. Biol. Psychiatry
32, 510 (2008),
Abstract;
Antioxidants from a Chinese medicinal herb - Psoralea corylifolia L.: G. Jiangning, et al.; Food Chem. 91, 287 (2005),
In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia: Y.C. Kim, et al.; Planta Med.
71, 87 (2005),
Abstract;
Antibacterial compounds from the seeds of Psoralea corylifolia: N.A. Khatune, et al.; Fitoterapia
75, 228 (2004),
Abstract;
Inducible flavone in oats (Avena sativa) is a novel defense against plant-parasitic nematodes: I.R. Soriano, et al.; Phytopathology
94, 1207 (2004),
Abstract;
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Cytotoxic constituents of Psoralea corylifolia: W. Mar, et al.; Arch. Pharm. Res.
24, 211 (2001),
Abstract;
Coumarins: A. Estevez-Braun & A.G. Gonzalez; Nat. Prod. Rep.
14, 465 (1997),
Abstract;
The cytotoxicity of psoralidin from Psoralea corylifolia: Y.M. Yang, et al.; Planta Med.
62, 353 (1996),
Abstract;
Influence of nitrogen on accumulation of isosojagol (a newly detected coumestan in soybean) and associated isoflavonoids in roots and nodules of mycorrhizal and non-mycorrhizal soybean: D. Morandi & J.L. Le Quere; New Phytol.
117, 75 (1991),
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