Antibiotic. Inhibitor of chitin synthase. Cytotoxic. Has nematicidal activity.
Product Details
Formula: | C22H25NO8 |
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MW: | 431.5 |
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Source: | Isolated from Aspergillus fumigatus. |
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CAS: | 58523-30-1 |
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Purity: | ≥98% (HPLC) |
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Identity: | Determined by 1H-NMR. |
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Appearance: | White to off-white powder. |
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Solubility: | Soluble in methanol or ethyl acetate; poorly soluble in water. |
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Shipping: | Ambient |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
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Handling: | After reconstitution protect from light at -20°C. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Fumiquinones A and B, nematicidal quinones produced by Aspergillus fumigatus: A. Hayashi, et al.; Biosci. Biotechnol. Biochem.
71, 1697 (2007),
Abstract;
Identification of a hybrid PKS/NRPS required for pseurotin A biosynthesis in the human pathogen Aspergillus fumigatus: S. Maiya, et al.; Chembiochem
8, 1736 (2007),
Abstract;
Directed biosynthesis of fluorinated pseurotin A, synerazol and gliotoxin: Y. Igarashi, et al.; J. Antibiot.
57, 748 (2004),
Abstract;
Novel neuritogenic activities of pseurotin A and penicillic acid: D. Komagata, et al.; J. Antibiot.
49, 958 (1996),
Abstract;