Less potent Na+/K+-ATPase inhibitor than other bufadienolides. Potent immunosuppressor.
Product Details
| Alternative Name: | (3β,5β,16β)-16-(Acetyloxy)-3-,14-dihydroxybufa-20,22-dienolide, 3β,14,16β-Trihydroxy-5β bufa-20,22-dienolide 16-acetate |
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| Formula: | C26H36O6 |
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| MW: | 444.6 |
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| Source: | Isolated from Bufonis venom. |
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| CAS: | 471-95-4 |
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| MI: | 14: 1477 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in 100% ethanol or chloroform. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The T-cell suppressive effect of bufadienolides: structural requirements for their immunoregulatory activity: P. Terness, et al.; Int. Immunopharmacol.
1, 119 (2001),
Abstract;
Bufadienolides from animal and plant sources: L. Krenn & B. Kopp; Phytochemistry
48, 1 (1999), (Review),
Abstract;
