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RNA polymerase II inhibitor
ALX-350-271-M001 1 mg 265.00 USD
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Biological activity like α-amanitin, but contains a carboxy group which is useful for coupling reactions.

Product Details

Alternative Name:EL-Amanitin
Source:Isolated from Amanita phalloides mushrooms.
MI:14: 373
Appearance:White to off-white powder.
Solubility:Soluble in DMF, DMSO, 100% methanol, and water.
Long Term Storage:-20°C
Use/Stability:Dilute with buffer immediately prior to use. Product is destroyed by concentrated acid or base.
Handling:Protect from light.
Regulatory Status:RUO - Research Use Only
ALX-350-271 structure
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ALX-350-271 structure

Product Literature References

An automated and highly sensitive chemiluminescence immunoassay for diagnosing mushroom poisoning: J. Zhu, et al.; Front. Chem. 9, 813219 (2021), Abstract; Full Text
First report of a neotropical Agaric (Lepiota spiculata, Agaricales, Basidiomycota) containing lethal α-amanitin at toxicologically relevant levels: C. Angelini, et al.; Front. Microbiol. 11, 1833 (2020), Abstract; Full Text
Highly sensitive determination of amanita toxins in biological samples using β-cyclodextrin collaborated molecularly imprinted polymers coupled with ultra-high performance liquid chromatography tandem mass spectrometry: L. Tan, et al.; J. Chromatogr. A 1630, 461514 (2020), Abstract;
Rapid, sensitive, and accurate point-of-care detection of lethal amatoxins in urine: C.S. Beyer, et al.; Toxins 12, 123 (2020), Abstract; Full Text
Toxin components and toxicological importance of Galerina marginata from Turkey: I. Akata, et al.; Toxicon 187, 29 (2020), Abstract;
A rapid extraction method combined with a monoclonal antibody-based immunoassay for the detection of amatoxins: C.S. Beyer, et al.; Toxins 11, 724 (2019), Abstract; Full Text
Two new species of Amanita sect. Phalloideae from Africa, one of which is devoid of amatoxins and phallotoxins: A. Fraiture, et al.; MycoKeys 53, 93 (2019), Abstract; Full Text
A new conjugation method used for the development of an immunoassay for the detection of amanitin, a deadly mushroom toxin: C.S. Beyer, et al.; Toxins 10, 265 (2018), Abstract; Full Text

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