Inhibits the growth of several Gram-positive and Gram-negative bacteria. Competitively inhibits muscarinic acetylcholine receptors.
Product Specification
| Formula: | C22H24Br2N10O2 . 2HCl |
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| MW: | 620.3 . 72.9 |
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| Source: | Isolated from the sponge Agelas nakamurai. |
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| CAS: | 79703-25-6 |
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| Purity: | ≥97% (HPLC) |
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| Identity: | Determined by 1H-NMR, 13C-NMR and MS. |
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| Appearance: | Amorphous powder. |
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| Solubility: | Soluble in DMSO or 100% ethanol. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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Product Literature References
Total synthesis of dimeric pyrrole-imidazole alkaloids: sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton: D.P. O'Malley, et al.; J. Am. Chem. Soc.
129, 4762 (2007),
Abstract;
Cyclic heptapeptides from the Jamaican sponge Stylissa caribica: R. Mohammed, et al.; J. Nat. Prod.
69, 1739 (2006),
Abstract;
New bromopyrrole alkaloids from the Indopacific sponge Agelas nakamurai: C. Eder, et al.; J. Nat. Prod.
62, 1295 (1999),
Abstract;
A study on the mechanism of action of sceptrin, an antimicrobial agent isolated from the South Pacific sponge Agelas mauritiana: V.S. Bernan, et al.; J. Antimicrob. Chemother.
32, 539 (1993),
Abstract;
Anti-muscarinic activity of a family of C11N5 compounds isolated from Agelas sponges: R. Rosa, et al.; Experientia
48, 885 (1992),
Abstract;
