Modulator of hepatic cytochrome P450 and phase II conjugation activity. The enzyme myrosinase transforms R-(-)-glucoraphanin into R-Sulforaphane (Prod. No. ALX-350-230).
Product Details
| Alternative Name: | 4-Methylsulfinylbutylglucosinate . K |
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| Formula: | C12H22NO10S3 . K . xH2O |
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| MW: | 436.5 . 39.1 (anhydrous basis) |
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| Source: | Isolated from Brassica oleracea var. palmifolia |
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| CAS: | 21414-41-5 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White solid. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Very hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products: M. Haack, et al.; Biol. Chem.
391, 1281 (2010),
Abstract;
Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice: A.T. Dinkova-Kostova, et al.; Photochem. Photobiol. Sci.
9, 597 (2010),
Abstract;
Intact glucosinolates modulate hepatic cytochrome P450 and phase II conjugation activities and may contribute directly to the chemopreventive activity of cruciferous vegetables: A.F. Abdull Razis, et al.; Toxicology
277, 74 (2010),
Abstract;
Evaluation of the safety and bioactivity of purified and semi-purified glucoraphanin: R.H. Lai, et al.; Food Chem. Toxicol.
46, 195 (2008),
Abstract;
