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R-(-)-Glucoraphanin . potassium salt

Cytochrome P450 modulator
 
ALX-350-181-M010 10 mg 327.00 USD
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Modulator of hepatic cytochrome P450 and phase II conjugation activity. The enzyme myrosinase transforms R-(-)-glucoraphanin into R-Sulforaphane (Prod. No. ALX-350-230).

Product Details

Alternative Name:4-Methylsulfinylbutylglucosinate . K
 
Formula:C12H22NO10S3 . K . xH2O
 
MW:436.5 . 39.1 (anhydrous basis)
 
Source:Isolated from Brassica oleracea var. palmifolia
 
CAS:21414-41-5
 
Purity:≥99% (HPLC)
 
Appearance:White solid.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Very hygroscopic.
 
Regulatory Status:RUO - Research Use Only
 
350-181
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350-181

Product Literature References

Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products: M. Haack, et al.; Biol. Chem. 391, 1281 (2010), Abstract;
Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice: A.T. Dinkova-Kostova, et al.; Photochem. Photobiol. Sci. 9, 597 (2010), Abstract;
Intact glucosinolates modulate hepatic cytochrome P450 and phase II conjugation activities and may contribute directly to the chemopreventive activity of cruciferous vegetables: A.F. Abdull Razis, et al.; Toxicology 277, 74 (2010), Abstract;
Evaluation of the safety and bioactivity of purified and semi-purified glucoraphanin: R.H. Lai, et al.; Food Chem. Toxicol. 46, 195 (2008), Abstract;

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