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Sarcophine

Inhibitor of ATPase and Acetylcholine esterase



ALX-350-166-M002	2 mg	253.00 USD
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Inhibitor of acetylcholine esterase and ATPase. Ichthyotoxin. Tumorigensis and JB6 cell transformation inhibitor.

Product Details

Formula:	C₂₀H₂₈O₃

MW:	316.4

Source:	Isolated from soft coral.

CAS:	55038-27-2

Purity:	≥96% (HPLC)

Identity:	Determined by ¹H-NMR.

Appearance:	White to off-white solid.

Solubility:	Soluble in methanol or dichlormethane.

Shipping:	Ambient Temperature

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Use/Stability:	Stable for at least 1 year after receipt when stored at -20°C.

Handling:	After reconstitution protect from light at -20°C.

Regulatory Status:	RUO - Research Use Only

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Product Literature References

HPLC method for the quantitative determination of sarcophine, a source of cembranoids with cancer chemopreventive activity: S.S. Bilasy, et al.; J. Pharm. Biomed. Anal. 46, 784 (2008), Abstract;

New cembranoid diterpenes from the Vietnamese soft coral Sarcophyton mililatensis stimulate osteoblastic differentiation in MC3T3-E1 cells: N.X. Cuong, et al.; Chem. Pharm. Bull. (Tokyo) 56, 988 (2008), Abstract; Full Text

Antiproliferative potential of sarcophine and its semisynthetic sulfur-containing derivatives against human mammary carcinoma cell lines: J.M. Arif, et al.; J. Nat. Med. 61, 154 (2007), Abstract;

Biocatalytic and antimetastatic studies of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine: S.S. Sawant, et al.; J. Nat. Prod. 69, 1010 (2006), Abstract;

Cembranoid diterpenes and a briarane diterpene from corals: D. Grote, et al.; Nat. Prod. Res. 20, 285 (2006), Abstract;

Structurally Novel Bioconversion Products of the Marine Natural Product Sarcophine Effectively Inhibit JB6 Cell Transformation: K.A. El Sayed, et al.; J. Org. Chem. 63, 7449 (1998), Abstract;

Inhibition of phosphofructokinase by the toxic cembranolide sarcophine isolated from the soft-bodied coral Sarcophyton glaucum: A. Erman & I. Neéman; Toxicon 15, 207 (1977), Abstract;

Sarcophine, a new epoxy cembranolide from marine origin: J. Bernstein, et al.; Tetrahedron 30, 2817 (1974),

Sarcophine--a new toxin from the soft coral Sarcophyton glaucum (Alcyonaria): I. Neeman, et al.; Toxicon 12, 593 (1974), Abstract;