Stable and water-soluble derivative of hyperforin inducing apoptosis. Antitumor agent. Inhibits sirtuins.
Product Details
| Formula: | C37H54O6 |
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| MW: | 594.8 |
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| CAS: | 849215-53-8 |
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| Purity: | ≥95% |
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| Identity: | Identity determined by MS, 1H- and 13C-NMR. |
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| Appearance: | White to yellow oil. |
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| Solubility: | Soluble in DMSO or 100mM sodium hydrogen carbonate/2% DMSO. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells: M. Šemeláková, et al.; Biomed. Pharmacother.
81, 38 (2016),
Application(s): Cell culture,
Abstract;
DNA-protective activities of hyperforin and aristoforin: A. Ševčovičová, et al.; Toxicol. In Vitro
29, 631 (2015),
Application(s): Assay,
Abstract;
Phloroglucinol Derivatives Guttiferone G, Aristoforin, and Hyperforin: Inhibitors of Human Sirtuins SIRT1 and SIRT2: C. Gey, et al.; Angew. Chem. Int. Ed. Engl.
46, 5219 (2007),
Abstract;
Aristoforin, a novel stable derivative of hyperforin, is a potent anticancer agent: M. Gartner, et al.; Chembiochem.
6, 171 (2005),
Abstract;
