Tobacco alkaloid. Potent nicotinic acetylcholine receptor agonist. Insecticide.
Product Details
| Alternative Name: | 3-(2-Piperidinyl)pyridine, 2-(3-Pyridyl)piperidine, Neonicotine |
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| Formula: | C10H14N2 . HCl |
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| MW: | 162.2 . 36.5 |
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| Source: | Isolated from Anabasis aphylla. |
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| CAS: | 15251-47-5 |
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| MI: | 14: 619 |
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| Purity: | ≥97% (TLC, NMR) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in alcohol or water. |
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| Shipping: | Ambient |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Anabasine toxicity from a topical folk remedy: N.G. Murphy, et al.; Clin. Pediatr. (Phila)
45, 669 (2006),
Abstract;
Anabasine, a selective nicotinic acetylcholine receptor agonist, antagonizes MK-801-elicited mouse popping behavior, an animal model of schizophrenia: J. Mastropaolo, et al.; Behav. Brain Res.
153, 419 (2004),
Abstract;
Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry: X. Xu, et al.; Clin. Chem.
50, 2323 (2004),
Abstract;
Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy: P. Jacob, 3rd, et al.; Cancer Epidemiol. Biomarkers Prev.
11, 1668 (2002),
Abstract;
Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro: R.L. Barbieri, et al.; J. Clin. Invest.
77, 1727 (1986),
Abstract;
