Inhibitor of EGFR tyrosine kinase with improved bioavailability over lavendustin C.
Product Specification
| Alternative Name: | Compound 5 methyl ester, 5-Amino-N-(2,5-dihydroxybenzyl)methyl salicylate |
| |
| Formula: | C15H15NO5 |
| |
| MW: | 289.3 |
| |
| Source: | Synthetic. |
| |
| Purity: | ≥97% |
| |
| Appearance: | Off-white solid. |
| |
| Solubility: | Soluble in DMSO or methanol. |
| |
| Shipping: | Ambient |
| |
| Long Term Storage: | -20°C |
| |
| Handling: | Protect from light. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Structure-activity relationships in a series of 5-[(2,5- dihydroxybenzyl)amino]salicylate inhibitors of EGF-receptor-associated tyrosine kinase: importance of additional hydrophobic aromatic interactions: H. Chen, et al.; J. Med. Chem.
37, 845 (1994),
Abstract;
Synthesis and structure-activity studies of a series of [(hydroxybenzyl)amino]salicylates as inhibitors of EGF receptor- associated tyrosine kinase activity: H. Chen, et al.; J. Med. Chem.
36, 4094 (1993),
Abstract;
