Extremely weak protein kinase C (PKC) activator. Starting material for synthesis of ingenol derivatives.
Product Details
| Formula: | C20H28O5 |
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| MW: | 348.4 |
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| CAS: | 30220-46-3 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in DMSO and 100% ethanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Total synthesis of ingenol: I. Kuwajima & K. Tanino; Chem. Rev.
105, 4661 (2005), (Review),
Abstract;
Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorbol esters, and ischaemia: S. Armstrong & C.E. Gonote; Cardiovasc. Res.
28, 1700 (1994),
Abstract;
Specific binding to protein kinase C by ingenol and its induction of biological responses: C.M. Hasler, et al.; Cancer Res.
52, 202 (1992),
Abstract;
