Hypolipidemic compound. PPARα (peroxisome proliferator-activated receptor α) agonist.
Product Details
| Alternative Name: | 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid |
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| Formula: | C13H14Cl2O3 |
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| MW: | 289.2 |
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| CAS: | 52214-84-3 |
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| MI: | 14: 2313 |
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| RTECS: | UF0880000 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to light yellow powder. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
P450 CYP2C epoxygenase and CYP4A ω-hydroxylase mediate ciprofibrate-induced PPARα-dependent peroxisomal proliferation: A. Gatica, et al.; J. Lipid Res.
48, 924 (2007),
Abstract;
Full Text
Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate: M.C. Clemencet, et al.; Cancer Lett.
222, 217 (2005),
Abstract;
Comparison of the effects of various peroxisome proliferators on peroxisomal enzyme activities, DNA synthesis, and apoptosis in rat and human hepatocyte cultures: V. Goll, et al.; Toxicol. Appl. Pharmacol.
160, 21 (1999),
Abstract;
Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate: P. Passilly, et al.; Biochem. Pharmacol.
58, 1001 (1999),
Abstract;
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