Selective, potent and cell permeable small molecule inhibitor of 11-β-hydroxysteroid dehydrogenase.
Product Details
Alternative Name: | N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide |
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Formula: | C24H33F3N4O2 |
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MW: | 466.5 |
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CAS: | 868604-75-5 |
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Purity: | ≥95% |
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Identity: | Identity determined by MS, 1H- and 13C-NMR. |
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Appearance: | White to off-white solid. |
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Solubility: | Soluble in DMSO. |
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Shipping: | Ambient |
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Long Term Storage: | -20°C |
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Handling: | Protect from light. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: J.J. Rohde, et al.; J. Med. Chem.
50, 149 (2007),
Abstract;
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