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BIX 01294 . trihydrochloride . hydrate

G9a histone methyltransferase inhibitor
 
ALX-270-473-M002 2 mg 264.00 USD
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Selective and cell permeable inhibitor of G9a histone methyltransferase.

Product Details

Formula:C28H38N6O2 . 3HCl . xH2O
 
MW:600.02
 
CAS:935693-62-2
 
Purity:≥95% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (5mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
Regulatory Status:RUO - Research Use Only
 
ALX-270-473 structure
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ALX-270-473 structure

Product Literature References

Inhibitory metaplasticity in juvenile stressed rats restores associative memory in the adulthood by regulating epigenetic complex G9a/GLP: R. Raghuraman, et al.; Int. J. Neuropsychopharmacol. (2022), Abstract;
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase: S. Kubicek, et al.; Mol. Cell 25, 473 (2007), Abstract;

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