Potent and reversible arginase inhibitor. Specifically interacts with the manganese-cluster of the arginase active site. Does not act as a substrate or as an inhibitor of NOS.
Product Details
| Alternative Name: | Nω-Hydroxy-nor-L-arginine . acetate |
| |
| Formula: | C5H12N4O3 . CH3COOH |
| |
| MW: | 176.2 . 60.1 |
| |
| CAS: | 189302-40-7 |
| |
| Purity: | ≥97% (TLC) |
| |
| Appearance: | White to slightly yellowish powder. |
| |
| Solubility: | Soluble in water (50mg/ml). |
| |
| Shipping: | Ambient Temperature |
| |
| Long Term Storage: | -20°C |
| |
| Handling: | Very hygroscopic. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression: K. Kiyofuji, et al.; Eur. J. Pharmacol.
760, 129 (2015),
Application(s): Cell Culture,
Abstract;
The new alpha-amino acid Nomega-hydroxy-nor-L-arginine: a high-affinity inhibitor of arginase well adapted to bind to its manganese cluster: J. Custot, et al.; JACS 119, 4086 (1997),
