Potent, selective and cell permeable inhibitor of phosphoinositide 3-kinase (PI(3)K) p110β.
Product Details
| Alternative Name: | 7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido-[1,2-a]pyrimidin-4-one |
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| Formula: | C21H24N4O2 |
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| MW: | 364.4 |
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| CAS: | 663619-89-4 |
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| Purity: | ≥98% (NMR) |
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| Appearance: | Pale yellow solid. |
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| Solubility: | Soluble in DMSO, 100% ethanol or dimethyl formamide; sparingly soluble in aqueous buffers. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
PI 3-kinase p110beta: a new target for antithrombotic therapy: S.P. Jackson, et al.; Nat. Med.
11, 507 (2005),
Abstract;
Full Text
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils: A.M. Condliffe, et al.; Blood
106, 1432 (2005),
Abstract;
Full Text
