Inhibitor of c-Src (IC50=0.43µM) blocking downstream STAT3 signalling. Induces apoptosis in human cancer cells.
Product Details
| Alternative Name: | E804 |
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| Formula: | C19H17N3O4 |
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| MW: | 351.4 |
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| Purity: | ≥96% (TLC) |
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| Identity: | Determined by 1H-NMR and 13C-NMR. |
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| Appearance: | Dark red solid. |
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| Solubility: | Soluble in DMSO (1M). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Effects of the Indirubin Derivative E804 on Glioblastoma Associated Immunomodulation: H. Houke; (2016), (master's thesis),
Application(s): Cytotoxicity assay and effects on protein expression,
Full Text
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells: S. Nam, et al.; PNAS
102, 5998 (2005),
Abstract;
