Replaces Prod. #: BML-FR105
Cell permeable derivative of vitamin E. Antioxidant. Inhibits peroxynitrite mediated tyrosine nitration and mitochondrial proton permeability. Prevents lipid peroxidation, cytotoxicity and apoptosis induced by cytochrome P450 2E1 in HEP G2 cells.
Product Details
| Alternative Name: | 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid |
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| Formula: | C14H18O4 |
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| MW: | 250.3 |
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| CAS: | 53188-07-1; 56305-04-5 |
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| RTECS: | DJ2273000 |
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| Purity: | ≥96.5% (Titration (T) NaOH 0.1M) |
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| Identity: | Determined by IR. |
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| Appearance: | White to off-white, pale yellow or pale green powder. |
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| Solubility: | Soluble in 100% ethanol (25mg/ml) or methanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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Closed-channel culture system for efficient and reproducible differentiation of human pluripotent stem cells into islet cells: K. Hirano, et al.; Biochem. Biophys. Res. Commun.
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Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer: J.L. Roh, et al.; Cancer Lett.
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Abstract;
Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells: Q. Chen et al.; Mol. Pharmacol.
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Abstract;
Inhibition of peroxynitrite dependent tyrosine nitration by hydroxycinnamates: nitration or electron donation?: A.S. Pannala et al.; Free Radic Biol Med
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Abstract;
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Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes [corrected]: M.G. Salgo, et al.; Arch. Biochem. Biophys.
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