Inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Neuroprotectant.
Product Details
Formula: | C7H7NO |
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MW: | 121.1 |
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CAS: | 55-21-0 |
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MI: | 14: 1060 |
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RTECS: | CU8700000 |
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Purity: | ≥98.5% (GC) |
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Identity: | Determined by IR. |
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Appearance: | White to off-white solid. |
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Solubility: | Soluble in 100% ethanol. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation: H. Kleine, et al.; Mol. Cell
32, 57 (2008),
Abstract;
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity: J. Zhang, et al.; Science
263, 687 (1994),
Abstract;
Cytotoxicity of a new IMP dehydrogenase inhibitor, benzamide riboside, to human myelogenous leukemia K562 cells: H.N. Jayaram, et al.; BBRC
186, 1600 (1992),
Abstract;