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PDE inhibitor
ALX-270-112-G005 5 g 44.00 USD
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Phosphodiesterase inhibitor. Blocks the synthesis of TNF-α. Improves blood flow by decreasing blood viscosity.

Product Details

Alternative Name:Trental, 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
Source:Isolated from Penicillium expansum.
MI:14: 7136
Purity:≥99% (HPLC)
Appearance:White to off-white crystalline powder.
Solubility:Soluble in water.
Shipping:Ambient Temperature
Long Term Storage:Ambient
Regulatory Status:RUO - Research Use Only
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Product Literature References

Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism: K. Prasad & P. Lee; Atherosclerosis 192, 313 (2007), Abstract;
Pentoxifylline: C.P. Samlaska & E.A. Winfield; J. Am. Acad. Dermatol. 30, 603 (1994), Review, Abstract;
Pentoxifylline inhibits the expression of tissue factor mRNA in endotoxin-activated human monocytes: V. Ollivier, et al.; FEBS Lett. 322, 231 (1993), Abstract;
Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality: P. Noel, et al.; Life Sci. 47, 1023 (1990), Abstract;