Selective inhibitor of protein kinase C (PKC).
Product Details
| Alternative Name: | (S)-2,6-diamino-N-{[1'-(1''-oxotridecyl)-2'-piperidinyl]methyl}hexanamide . 2HCl |
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| Formula: | C25H50N4O2 . 2 HCl |
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| MW: | 511.6 |
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| CAS: | 136449-85-9; 141774-20-1 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water, DMSO or methanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
2,6-Diamino-N-([1-(1-oxotridecyl)-2-piperidinyl] methyl)hexanamide (NPC 15437): a novel inhibitor of protein kinase C interacting at the regulatory domain: J.P. Sullivan, et al.; Mol. Pharmacol.
41, 38 (1992),
Abstract;
2,6-Diamino-N-([1-oxotridecyl)-2-piperidinyl]methyl)hexanamide (NPC 15437): a selective inhibitor of protein kinase C: J.P. Sullivan, et al.; Agents Actions
34, 142 (1991),
Abstract;
NPC 15437 interacts with the C1 domain of protein kinase C. An analysis using mutant PKC constructs: J.P. Sullivan, et al.; FEBS Lett.
285, 120 (1991),
Abstract;
