Replaces Prod. #: BML-EI133
Cyclooxygenase (COX) inhibitor. Widely used non-steroidal anti-inflammatory drug.
Product Details
| Alternative Name: | (S)-6-Methoxy-α-methyl-2-naphthalene acetic acid |
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| Formula: | C14H14O3 |
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| MW: | 230.3 |
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| CAS: | 22204-53-1 |
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| MI: | 14: 6417 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white crystalline powder. |
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| Solubility: | Soluble in DMSO, dimethyl formamide and 100% ethanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Nonsteroidal anti-inflammatory drug naproxen destabilizes Abeta amyloid fibrils: a molecular dynamics investigation: T. Takeda, et al.; J. Phys. Chem. B.
114, 15394 (2010),
Abstract;
Full Text
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma: M. Sastre, et al.; PNAS U.S.A.
103, 443 (2006),
Abstract;
Full Text
Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): rationale for selective inhibition and progress to date: D.E. Griswold & J.L. Adams; Med. Res. Rev.
16, 181 (1996),
Abstract;
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs: O. Laneuville, et al.; J. Pharmacol. Exp. Ther.
271, 927 (1994),
Abstract;
Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system: J. Barnett, et al.; Biochim. Biophys. Acta
1209, 130 (1994),
Abstract;
Perspectives in nonsteroidal anti-inflammatory agents: T.Y. Shen; Angew. Chem. Int. Ed.
11, 460 (1972),
Abstract;
