Inhibitor of myosin light chain kinase, cAMP-dependent protein kinase (PKA) and protein kinase C (PKC).
Product Details
| Alternative Name: | 1-(5-Isoquinolinylsulfonyl)piperazine . 2HCl |
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| Formula: | C13H15N3O2S . 2HCl |
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| MW: | 350.3 |
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| CAS: | 84468-24-6 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | Off-white lyophilized solid. |
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| Solubility: | Soluble in water or DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives: M. Hagiwara, et al.; Mol. Pharmacol.
32, 7 (1987),
Abstract;
Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor: C. Gerard, et al.; J. Clin. Invest.
77, 61 (1986),
Abstract;
