Nitric oxide synthase (NOS) inhibitor, relatively selective for inducible nitric oxide synthase (iNOS/NOS II).
Product Details
| Alternative Name: | S-(3-Aminopropyl)isothiourea . 2HBr, 2-(3-Aminopropyl)-2-thiopseudourea . 2HBr |
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| Formula: | C4H11N3S . 2HBr |
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| MW: | 133.2 . 161.8 |
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| Purity: | ≥98% |
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| Appearance: | Off-white solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
C57BL/6N Mice Are More Resistant to Ehrlich Ascites Tumors Than C57BL/6J Mice: The Role of Macrophage Nitric Oxide: S. Kalish, et al.; Med. Sci. Monit. Basic Res.
21, 235 (2015),
Application(s): NO production,
Abstract;
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity: G.J. Southan, et al.; Br. J. Pharmacol.
114, 510 (1995),
Abstract;
Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas: E.P. Garvey, et al.; J. Biol. Chem.
269, 26669 (1994),
Abstract;
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