Inhibitor of nitric oxide synthase (NOS). 10 times more potent than S-Methyl-ITU (Prod. No. ALX-270-027).
Product Specification
| Alternative Name: | S-Isopropylisothiourea . HBr, 2-Isopropyl-2-thiopseudourea . HBr |
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| Formula: | C4H10N2S . HBr |
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| MW: | 199.1 |
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| CAS: | 4269-97-0 |
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| Purity: | ≥98% |
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| Appearance: | White crystalline powder. |
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| Solubility: | Soluble in PBS, pH 7.2 (30mg/ml), 100% ethanol (100mg/ml), DMSO (200mg/ml) or dimethyl formamide (50mg/ml). |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least one year when stored at -20°C. We do not recommend storing the aqueous solution for more than one day. |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity: G.J. Southan, et al.; Br. J. Pharmacol.
114, 510 (1995),
Abstract;
Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas: E.P. Garvey, et al.; J. Biol. Chem.
269, 26669 (1994),
Abstract;
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