Replaces Prod. #: BML-CN259
Potent and selective inhibitor of inducible nitric oxide synthase (iNOS; NOS II). Ki (iNOS)=47nM, Ki (eNOS)=9.0μM.
Product Details
| Alternative Name: | S,S'-(1,3-Phenylene-bis(1,2-ethanediyl))bis-isothiourea . 2HBr, PBITU |
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| Formula: | C12H18N4S2 . 2HBr |
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| MW: | 444.2 |
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| Purity: | ≥97% |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in water (25mg/ml). |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Real-time electrochemical detection of extracellular nitric oxide in tobacco cells exposed to cryptogein, an elicitor of defence responses: A. Besson-Bard, et al.; J. Exp. Bot.
59, 3407 (2008),
Abstract;
Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas: E.P. Garvey, et al.; J. Biol. Chem.
269, 26669 (1994),
Abstract;
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