Replaces Prod. #: BML-CN258
Selective inhibitor of inducible nitric oxide synthase (iNOS; NOS II). Shows anti-inflammatory activity.
Product Details
| Alternative Name: | L-N6-(1-Iminoethyl)-lysine . 2HCl |
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| Formula: | C8H17N3O2 . 2HCl |
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| MW: | 187.2 . 73.0 |
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| CAS: | 159190-45-1 |
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| Purity: | ≥97% (TLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | 100mg/ml soluble in water or methanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Very hygroscopic. Keep under inert gas. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor-Dependent Death of Retinal Endothelial Cells: JC. Portillo, et al.; Invest. Ophthalmol. Vis. Sci.
1, 6278 (2016),
Abstract;
Full Text
Adiponectin is a potential catabolic mediator in osteoarthritis cartilage: E.H. Kang, et al.; Arthritis Res. Ther.
12, R231 (2010),
Abstract;
Full Text
Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors: D. Salvemini, et al.; J. Clin. Invest.
96, 301 (1995),
Abstract;
L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase: W.M. Moore, et al.; J. Med. Chem.
37, 3886 (1994),
Abstract;
