Irreversible, cell permeable inhibitor of caspase-1 and -5. Inhibits also caspase-4 and-14. Designed as a methyl ester to facilitate cell permeability.
Product Details
| Alternative Name: | Caspase-1 inhibitor (fluoromethylketone), Caspase-5 inhibitor (fluoromethylketone) |
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| Sequence: | Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone |
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| Formula: | C37H42FN7O11 |
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| MW: | 763.8 |
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| Formulation: | Liquid. In DMSO. |
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| Purity: | ≥99% (HPLC) |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Technical Info/Product Notes: | We recommend a final concentration of 2µM for inhibiting caspase activity in Jurkat cell culture. The optimal doses may vary for different cells and culture conditions. |
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| Regulatory Status: | RUO - Research Use Only |
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