Irreversible, cell permeable inhibitor of caspase-2.
Product Details
| Alternative Name: | Caspase-2 inhibitor (fluoromethylketone) |
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| Sequence: | Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone |
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| Formula: | C32H46FN5O11 |
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| MW: | 695.7 |
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| Purity: | ≥99% (TLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store stock solutions in aliquots at -20°C. |
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| Handling: | Keep cool and dry. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Distinct pathways for stimulation of cytochrome c release by etoposide: J.D. Robertson, et al.; J. Biol. Chem.
275, 32438 (2000),
Abstract;
Full Text
Function of caspases in regulating apoptosis caused by erythropoietin deprivation in erythroid progenitors: P.A. Gregoli & M.C. Bondurant; J. Cell Physiol.
178, 133 (1999),
Abstract;
Substrate specificities of caspase family proteases: R.V. Talanian, et al.; J. Biol. Chem.
272, 9677 (1997),
Abstract;
Full Text
