Fluorogenic substrate for caspase-3.
Product Details
| Alternative Name: | Caspase-3 substrate (fluorogenic) |
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| Sequence: | Ac-Asp-Met-Gln-Asp-AMC (AMC=7-Amino-4-methylcoumarin) |
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| Formula: | C30H38N6O12S |
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| MW: | 706.7 |
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| Peptide Content: | 75-95%. |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in DMSO. Dilute with distilled water or buffer. Also soluble in phosphate buffer, pH 7.5 |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Handling: | Keep cool and dry. |
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| Technical Info/Product Notes: | AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Myostatin gene inactivation increases post-mortem calpain-dependent muscle proteolysis in mice: R. Nassar, et al.; Meat Sci.
185, 108726 (2022),
Abstract;
CRISPR knock out of programmed cell death protein 1 enhances anti-tumor activity of cytotoxic T lymphocytes: Z. Zhao, et al. ; Oncotarget
9, 5208 (2018),
Abstract;
Full Text
Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells: J. Hofmanova; Eur. J. Nutrition
44, 40 (2005),
Abstract;
Bid truncation, bid/bax targeting to the mitochondria, and caspase activation associated with neutrophil apoptosis are inhibited by granulocyte colony-stimulating factor: N.A. Maianski, et al.; J. Immunol.
172, 7024 (2004),
Abstract;
The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status: M. Kovarikova, et al.; Differentiation
72, 23 (2004),
Abstract;
