Fluorogenic substrate for caspase-8 and granzyme B with increased cell permeability. Also substrate for caspase-10.
Product Details
| Alternative Name: | Caspase-8 substrate (chromogenic), Granzyme B substrate (chromogenic) |
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| Sequence: | Z-Ile-Glu-Thr-Asp-pNA (pNA = p-Nitroaniline) |
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| Formula: | C33H42N6O13 |
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| MW: | 730.7 |
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| Formulation: | Lyophilized. |
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| Peptide Content: | 70-90% |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in DMSO (1 mg/ml). Further dilutions can be made in aqueous buffer. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Keep cool and dry. |
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| Technical Info/Product Notes: | λmax of pNA is 400nm. |
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| Regulatory Status: | RUO - Research Use Only |
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