Replaces Prod. #: BML-P413
Reversible inhibitor of caspase-3 and -7. Useful for the purification or extract depletion of caspase-3 in conjunction with streptavidin conjugates.
Product Details
| Alternative Name: | Caspase-3 inhibitor (aldehyde), Caspase-7 inhibitor (aldehyde), CPP32 affinity reagent |
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| Sequence: | Biotinyl-Asp-Glu-Val-Asp-CHO |
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| Formula: | C28H42N6O12S |
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| MW: | 686.7 |
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| Formulation: | Lyophilized. |
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| Peptide Content: | 65-90%. |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in 50% acetic acid with agitation (1mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Packaged under inert gas. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis: D.W. Nicholson, et al.; Nature
376, 37 (1995),
Abstract;
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE: Y.A. Lazebnik, et al.; Nature
371, 346 (1994),
Abstract;
