Replaces Prod. #: BML-P401
Fluorogenic caspase-1 substrate with a Km=14µM. Ex.:340-360nm, Em.:440-460nm.Sequence is based on precursor interleukin-1β Asp116 cleavage site for caspase-1.
Product Details
| Alternative Name: | Caspase-1 substrate (fluorogenic) |
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| Sequence: | Ac-Tyr-Val-Ala-Asp-AMC (AMC = 7-Amino-4-methylcoumarin) |
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| Formula: | C33H39N5O10 |
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| MW: | 665.7 |
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| Peptide Content: | 75-95% |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in DMSO. Dilute with distilled water or buffer, pH 7.0-7.5 (e. g. TRIS, HEPES). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. Keep cool and dry. |
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| Technical Info/Product Notes: | AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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Application(s): Caspase-1 activity in mouse heart homogenates,
Abstract;
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