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Substrate for caspase-1 and -4
ALX-260-023-M001 1 mg 398.00 USD
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Specific, highly fluorescent substrate for caspase-1. Also substrate for caspase-4.

Product Details

Alternative Name:Caspase-1 substrate (fluorogenic)
Sequence:Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH (Mca = (7-Methoxycoumarin-4-yl)acetyl; Dnp = Dinitrophenyl)
Purity:≥97% (HPLC)
Appearance:White to yellow powder.
Solubility:Soluble in DMSO or 80% acetic acid (1mg/ml, with agitation).
Shipping:Ambient Temperature
Long Term Storage:-20°C
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
Technical Info/Product Notes:Mca has an excitation maximum of 325nm and an emission maximum of 392nm.
Regulatory Status:RUO - Research Use Only

Product Literature References

Sequential activation of ICE-like and CPP32-like proteases during Fas- mediated apoptosis: M. Enari, et al.; Nature 380, 723 (1996), Abstract;