Replaces Prod. #: BML-PI131
Potent and specific inhibitor of cathepsin B in vitro and in vivo. Free acid form used in vitro or in isolated enzyme studies but not in whole cells. Can discriminate between cathepsin B and L/S forms.
Product Details
| Alternative Name: | N-[L-3-trans-Propylcarbamoyloxirane-2-carbonyl]-Ile-Pro-OH |
| |
| Formula: | C18H29N3O6 |
| |
| MW: | 383.5 |
| |
| CAS: | 134448-10-5 |
| |
| Purity: | ≥98% (HPLC) |
| |
| Appearance: | White to off-white powder. |
| |
| Solubility: | Soluble in ethyl acetate (50mg/ml) or DMSO. |
| |
| Shipping: | Ambient Temperature |
| |
| Long Term Storage: | -20°C |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Fluorometric microassays for the determination of cathepsin L and cathepsin S activities in tissue extracts: B. Werle, et al.; Biol. Chem.
380, 1109 (1999),
Abstract;
Specific assay method for the activities of cathepsin L-type cysteine proteinases: T. Inubushi, et al.; J. Biochem.
116, 282 (1994),
Abstract;
Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo: T. Towatari, et al.; FEBS Lett.
280, 311 (1991),
Abstract;
Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro: M. Murata, et al.; FEBS Lett.
280, 307 (1991),
Abstract;
