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ZBP1 (human) polyclonal antibody (AT133)

ALX-210-959-C100 100 µg 320.00 USD
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Product Specification

Alternative Name:DAI, DNA-dependent activator of IFN-regulatory factors, Z-DNA-binding protein 1, Tumor stroma and activated macrophage protein DLM-1
Immunogen:Recombinant human ZBP1 (aa 1-429).
UniProt ID:Q9H171
Species reactivity:Human
Applications:IP, WB
Recommended Dilutions/Conditions:Immunoprecipitation (1:200)
Western blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein A-affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Shipping:Shipped on Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Scientific Background:ZBP1  is a cytoplasmic recognition receptor that senses and is activated by DNA from several sources. Upon activation, ZBP1 triggers a type I IFN response through the activation of IRF3 and, probably, IRF7.
Regulatory Status:RUO - Research Use Only

General Literature References

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response: A. Takaoka, et al.; Nature 448, 501 (2007), Abstract;

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