Product Details
Alternative Name: | Tumor related protein, C1orf10 gene product, Chromosome 1 open reading frame 10 gene product |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to aa 259-274 (E259ATNDQNRGTETHGQG274) of human cornulin. |
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UniProt ID: | Q99627 |
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Species reactivity: | Human
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Applications: | IHC, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (frozen sections, 1:100) Western Blot (1:2,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~70kDa by Western blot. |
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Purity Detail: | Immunoaffinity purified. |
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Formulation: | Liquid. In PBS containing 1% BSA and 0.01% sodium azide. |
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Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Figure: Immunodetection of human cornulin using PAb to Cornulin (human) (SZ1229) (Prod. No.
ALX-210-922).
Method: Staining performed on frozen sections of esophagus (A-B), foreskin (C-D) and scalp (D-E) using PAb to cornulin at 1:100 in PBS containing 12% BSA. Cornulin is expressed in the outer most layer of scalp skin and in the inner root sheat of the hair follicle, in normal esophagus, the staining is localized in the upper spinous and granular layers with strong peripheral localization. Control sections (B,D,E) show no staining. Basal layer is indicated (solid red line) [see 1]."
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Product Literature References
Cornulin, a new member of the "fused gene" family, is expressed during epidermal differentiation: R. Contzler, et al.; J. Invest. Dermatol.
124, 990 (2005),
Abstract;