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PARP-1 (human) polyclonal antibody

 
ALX-210-895-R100 100 µl 205.00 USD
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Product Details

Alternative Name:Poly(ADP-ribose) polymerase-1
 
Host:Rabbit
 
Immunogen:Recombinant human PARP-1 (poly(ADP-ribose) polymerase-1) (aa 215-525).
 
UniProt ID:P09874
 
Species reactivity:Human
 
Crossreactivity:Weakly cross-reacts with mouse and monkey PARP-1.
 
Applications:ICC, IHC, IP, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (1:500-1:1,000)
Immunohistochemistry (1:500-1:1,000)
Immunoprecipitation (2µl per 100µg nuclear extract)
Western Blot (1:2,000-1:5,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Formulation:Liquid. Antiserum containing 0.1% sodium azide.
 
Use/Stability:Stable for 1 week when stored at +4°C.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
 
Shipping:Dry Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-80°C
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

Acetylation of PARP-1 by p300/CBP regulates coactivation of NF-kappa B-dependent transcription: P.O. Hassa, et al.; J. Biol. Chem. 280, 40450 (2005), Abstract; Full Text
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice: V. Petrilli, et al.; J. Clin. Invest. 114, 1072 (2004), Abstract; Full Text

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The PARP Family & ADP Ribosylation
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