Replaces Prod. #: ALX-210-785/1
Product Details
Alternative Name: | VDAC, Mitochondrial porin |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to a part (CNDGTEFGGSIYQK) of C-terminal human VDAC (voltage-dependent anion channel) with an added N-terminal cysteine. This sequence is completely conserved between isoforms 1, 2 and 3 of human, mouse and rat VDAC. |
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UniProt ID: | P21796 |
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Species reactivity: | Human, Mouse, Rat Monkey
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Applications: | IP, WB
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Recommended Dilutions/Conditions: | Western Blot (2µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~31kDa by Western blot. |
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Purity Detail: | Epitope-affinity purified IgG. |
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Formulation: | Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondria: M.R. Brown, et al.; J. Biol. Chem.
281, 11658 (2006),
Abstract;
Full Text
Modulation of mitochondrial transition pore components by thyroid hormone: E. Yehuda-Shnaidman, et al.; Endocrinology
146, 2462 (2005),
Abstract;
Full Text
Proteome analysis of DNA damage-induced neuronal death using high throughput mass spectrometry: M.D. Johnson, et al.; J. Biol. Chem.
279, 26685 (2004),
Abstract;
Full Text
Phospholipid scramblase 3 controls mitochondrial structure, function, and apoptotic response: J. Liu, et al.; Mol. Cancer Res.
1, 892 (2003),
Abstract;
Full Text
General Literature References
The mitochondrial permeability transition pore and its role in cell death: M. Crompton; Biochem. J.
341 (Pt 2), 233 (1999), Review,
Abstract;
Full Text