Product Details
Alternative Name: | C-C chemokine receptor 4, CD194 |
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Host: | Goat |
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Immunogen: | Synthetic peptide corresponding to aa 18-39 (S18NYYLYESIPK PCTKEGIKAFGE39) of human CCR4 (C-C chemokine receptor 4). |
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UniProt ID: | P51679 |
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Species reactivity: | Human
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Applications: | ICC, IHC (PS), WB
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Recommended Dilutions/Conditions: | Immunocytochemistry (acetone fixed cells, 1:400) Immunohistochemistry (paraffin sections, 1:200) Western Blot (1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Epitope-affinity purified IgG. |
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Quality Control: | Immunocytochemistry on mouse spleen cells. |
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Formulation: | Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide. |
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Handling: | For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Mouse CCR4 is the homolog of human CCR4 receptor (85% identical), binding macrophage inflammatory protein-1α (MIP-1α) and RANTES. Mouse CCR4 transcripts are expressed in the thymus and in T-cell lines. |
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Regulatory Status: | RUO - Research Use Only |
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Figure: Immunohistochemistry on paraffin sections of human spleen cells using PAb to CCR4 (human) (Prod No.
ALX-210-622)."
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General Literature References
Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4: A. Hoogewerf, et al.; BBRC
218, 337 (1996),
Abstract;