Product Details
| Alternative Name: | TNFRSF 21, Death receptor-6 |
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| Host: | Rabbit |
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| Immunogen: | Recombinant human DR6 (TNFRSF 21) (aa 370-655). |
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| UniProt ID: | O75509 |
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| Species reactivity: | Human
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| Applications: | ICC, WB
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| Recommended Dilutions/Conditions: | Immunocytochemistry (3µg/ml)
Western Blot (1µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Formulation: | Liquid. In PBS. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Figure 1: Immunodetection of transfected human DR6 in HEK 293 cells using PAb to DR6 (human) (Prod. No.
ALX-210-569). Asteriks represent N-glycosylated forms and arrow shows unglycosylated form of DR6."
Figure 2: Immunocytochemical analysis of transfected human DR6 in HEK 293 cells using PAb to DR6 (human) (Prod. No.
ALX-210-569). Confocal microscopy shows membrane localization of DR6; nuclei stained with DRAQ5 (Prod. No.
BOS-889-001)."
Figure 3: Immunodetection of endogenous human DR6 in hematopoietic cells using PAb to DR6 (human) (Prod. No.
ALX-210-569). Arrow represents unglycosylated form and asteriks shows alternatively translated form of DR6."
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Product Literature References
T-cell activation triggers death receptor-6 expression in a NF-kappaB and NF-AT dependent manner: M. Klima, et al.; Mol. Immunol.
48, 1439 (2011),
Abstract;
Functional analysis of the posttranslational modifications of the death receptor 6: M. Klima, et al.; Biochim. Biophys. Acta
1793, 1579 (2009),
Abstract;
