Product Details
Host: | Rabbit |
|
Immunogen: | Synthetic peptide corresponding to aa 222-240 (D222CDPRSIHVREDGSLEIGD240) of N-terminal human UBE1L. |
|
UniProt ID: | P41226 |
|
Species reactivity: | Human
|
|
Applications: | IHC (FS), IHC (PS), WB
|
|
Formulation: | Liquid. Raw antiserum. Contains no preservatives. |
|
Handling: | Avoid freeze/thaw cycles. |
|
Shipping: | Shipped on Blue Ice |
|
Long Term Storage: | -20°C |
|
Scientific Background: | Human UBE1L shows a 45% homology to the human ubiquitin-activating enzyme E1 at the amino acid level. UBE1L is a retinoid target that triggers promyelocytic leukemia (PML)/ all trans-retinoic acid receptor α (RARα) degradation in acute promyelocytic leukemia. |
|
Regulatory Status: | RUO - Research Use Only |
|
Product Literature References
UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia: S. Kitareenwan, et al.; PNAS
99, 3806 (2002),
Abstract;