Product Specification
| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to aa 222-240 (D222CDPRSIHVREDGSLEIGD240) of N-terminal human UBE1L. |
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| UniProt ID: | P41226 |
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| Species reactivity: | Human
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| Applications: | IHC (FS), IHC (PS), WB
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| Formulation: | Liquid. Raw antiserum. Contains no preservatives. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Human UBE1L shows a 45% homology to the human ubiquitin-activating enzyme E1 at the amino acid level. UBE1L is a retinoid target that triggers promyelocytic leukemia (PML)/ all trans-retinoic acid receptor α (RARα) degradation in acute promyelocytic leukemia. |
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Product Literature References
UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia: S. Kitareenwan, et al.; PNAS
99, 3806 (2002),
Abstract;
