Product Details
Alternative Name: | ERα |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to aa 1-21 (M1TMTLHTKASGMALLHQIQGN21) of N-terminal human ERα (estrogen receptor α). This sequence is completely conserved in rat and mouse ERα and is highly conserved in sheep, pig, dog, bovine and chicken ERα. |
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UniProt ID: | P03372 |
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Species reactivity: | Human, Rat
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Specificity: | Recognizes endogenous ERα. |
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Crossreactivity: | Does not cross-react with ERβ. |
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Applications: | IHC (FS), WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (frozen sections, 1-5µg/ml) Western Blot (1µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~64kDa by Western blot. |
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Purity Detail: | Epitope-affinity purified IgG. |
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Formulation: | Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Figure: Immunohistochemistry of ERa in rat prostate using PAb to Estrogen Receptor a (Prod. No.
ALX-210-201)."
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Product Literature References
Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast: R.K. Dubey, et al.; J. Clin. Endocrinol. Metab.
90, 247 (2005),
Abstract;
Full Text
Differential Regulation of Estrogen Receptor Subtypes alpha and beta in Human Aortic Smooth Muscle Cells by Oligonucleotides and Estradiol: F. Barchiesi, et al.; J. Clin. Endocrinol. Metab.
89, 2373 (2004),
Abstract;