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PPARγ2 (mouse) polyclonal antibody

ALX-210-192-R100 100 µl 772.00 USD
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Product Details

Alternative Name:Peroxisome proliferator activated receptor γ2
Immunogen:Synthetic peptide corresponding to aa 1-16 (M1GETLGDSPIDPESDS16) of human PPARγ2 (peroxisome proliferator activated receptor γ2). 
UniProt ID:P37231
Species reactivity:Mouse
Crossreactivity:Does not cross-react with PPARα or PPARδ.
Applications:ICC, IHC, WB, FUNC
Gel Supershift
Recommended Dilutions/Conditions:Immunocytochemistry (1:500)
Immunohistochemistry (1:500)
Western Blot (1:500)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Functional Application: Inhibits PPARγ2 DNA binding
Detects a band of ~56kDa by Western blot.
Purity Detail:Epitope-affinity purified IgG.
Formulation:Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Endoplasmic reticulum-mitochondrial interaction mediated by Mitofusin-1 or Mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation: P.J. McFie, et al.; Biochem. Biophys. Res. Commun. 478, 392 (2016), Application(s): Immunoblot analysis, Abstract;
Peroxisome proliferator-activated receptor α and γ agonists differently regulate classical and alternative macrophage activation: E.L. Paukkeri, et al.; Immunometabolism 2, 1 (2015), Application(s): Western Blot, Full Text
The effect of neuronal conditional knock-out of peroxisome proliferator-activated receptors in the MPTP mouse model of Parkinson's disease: R.B. Mounsey, et al.; Neuroscience 300, 576 (2015), Application(s): Immunofluorescence, Abstract;
A human peripheral blood monocyte-derived subset acts as pluripotent stem cells: Y. Zhao, et al.; PNAS 100, 2426 (2003), Abstract; Full Text
Activation of peroxisome proliferator-activated receptor gamma by nitric oxide in monocytes/macrophages down-regulates p47phox and attenuates the respiratory burst: A. Von Knethen & B. Brune; J. Immunol. 169, 2619 (2002), Abstract; Full Text
Delayed activation of PPARgamma by LPS and IFN-gamma attenuates the oxidative burst in macrophages: A.A. Von Knethen & B. Brune; FASEB J. 15, 535 (2001), Abstract; Full Text
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes: R.M. Lavinsky, et al.; PNAS 95, 2920 (1998), Abstract; Full Text

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